SCLERODERMA LIKE GRAFT VERSUS HOST DISEASE (GVHD): A LATE CONSEQUENCE OF BONE HARROW GRAFTING

Treatment of chronic cutaneous graft versus host disease (GVHD) with photochemotherapy with Psoralen (PUVA): A report of five cases

Chronic graft versus host disease (GVHD) remains the most common late complication of allogenic stem cell transplantation and the most frequent cause of morbidity and mortality in these patients. To control this condition, immunosuppressive drugs are usually administered at a high dose and for a long time, which may result in several side effects. 5 patients with clinically and histopathologica...

Graft-versus-host disease or graft-versus-host-like syndrome.

Management of acute graft versus host disease (GvHD).

Graft versus host disease (GvHD) is a frequent complication of allogeneic hemopoietic stem cell transplantation (HSCT), and of donor lymphocyte infusions (DLI): the acute form occurs within 100 days from HSCT or DLI, the chronic form beyond day +100. GvHD should be prevented rather than treated. There are several ways to prevent GvHD: remove donor T cells from the transplant (ex vivo T-cell dep...

Graft - Versus - Host - Like Disease - A

Graft-versus-host disease (GVHD) is a T-cell-mediated reaction that most commonly develops after transplantation of hematopoietic stem cells. In rare conditions, GVHD-like symptoms are observed in patients with thymoma. We present the case of a 58-year-old man with thymoma noted 6 years earlier who initially presented with myasthenia gravis and subsequently developed GVHD-like disease with symp...

Novel Treatment Concepts for Graft versus Host Disease ( GvHD )

Acute and chronic graft versus host disease (GvHD) are potentially lethal complications after stem cell transplantation (SCT). Steroids are the appropriate first-line treatment for both. However, if patients do not adequatly benefit from steroid therapy, mortality is high and standardized treatment algorithms are lacking. This is mainly due to limited data from prospective, randomized clinical ...